human v2.0 mirna expression beadchip microarray platform (Illumina Inc)
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Human V2.0 Mirna Expression Beadchip Microarray Platform, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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1) Product Images from "MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview"
Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview
Journal: Molecular Neurobiology
doi: 10.1007/s12035-014-8668-y
Figure Legend Snippet: The biogenesis of miRNA requires RNA polymerase II/III for the transcription of pri-miRNA. The pri-miRNA product is then cleaved by the Drosha-DGCR8 complex into pre-miRNA. The pre-miRNA is exported to the cytoplasm by Exportin-5 in the presence of Ran-GTP co-factor. Once in the cytoplasm, the pre-miRNA is cleaved by the Dicer-TRBP complex into a miRNA duplex, which is unwound into two products: a guide strand bound to Ago2, which is incorporated into the RISC, and a passenger strand, which is degraded. Finally, the miRNA binds to its target mRNAs resulting in mRNA target cleavage, translational repression, or mRNA decay. A more novel fate of the miRNAs is the selective secretion via microvesicles or exosomes. Ran = Ras-related nuclear protein; GTP = guanosine-5′-triphosphate; TRBP = TAR (HIV-1) RNA binding protein; Ago2 = Argonaute protein 2; RISC = RNA-induced silencing complex
Techniques Used: RNA Binding Assay
Figure Legend Snippet: Studies performed on dataset obtained from public databases
Techniques Used: Biomarker Discovery, In Vitro, Cell Culture, Activity Assay, Standard Deviation, Expressing, Software, Mutagenesis, Amplification
Figure Legend Snippet: Studies performed on independent tissue cohorts
Techniques Used: Control, Biomarker Discovery, In Situ Hybridization, In Vitro, In Situ, Methylation, Expressing, Invasion Assay, Transfection, Amplification, Migration, Luciferase, Transwell Assay, Wound Healing Assay
Figure Legend Snippet: miRNAs reported to be protective or risk-associated
Techniques Used: Expressing
Figure Legend Snippet: miRNA signatures correlating with survival in GBM
Techniques Used:
Related Articles
Expressing:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Microarray:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the RNA Binding Assay:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Biomarker Discovery:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the In Vitro:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Cell Culture:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Activity Assay:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Standard Deviation:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Software:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Mutagenesis:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Amplification:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Control:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the In Situ Hybridization:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the In Situ:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Methylation:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Invasion Assay:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Transfection:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Migration:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Luciferase:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Transwell Assay:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Wound Healing Assay:Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the |