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human v2.0 mirna expression beadchip microarray platform  (Illumina Inc)


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    Structured Review

    Illumina Inc human v2.0 mirna expression beadchip microarray platform
    The biogenesis of <t>miRNA</t> requires RNA polymerase II/III for the transcription of pri-miRNA. The pri-miRNA product is then cleaved by the Drosha-DGCR8 complex into pre-miRNA. The pre-miRNA is exported to the cytoplasm by Exportin-5 in the presence of Ran-GTP co-factor. Once in the cytoplasm, the pre-miRNA is cleaved by the Dicer-TRBP complex into a miRNA duplex, which is unwound into two products: a guide strand bound to Ago2, which is incorporated into the RISC, and a passenger strand, which is degraded. Finally, the miRNA binds to its target mRNAs resulting in mRNA target cleavage, translational repression, or mRNA decay. A more novel fate of the miRNAs is the selective secretion via microvesicles or exosomes. Ran = Ras-related nuclear protein; GTP = guanosine-5′-triphosphate; TRBP = TAR (HIV-1) RNA binding protein; Ago2 = Argonaute protein 2; RISC = RNA-induced silencing complex
    Human V2.0 Mirna Expression Beadchip Microarray Platform, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+v2%2E0+mirna+expression+beadchip+microarray+platform/pmc04225053-216-17-16?v=Illumina+Inc
    Average 90 stars, based on 1 article reviews
    human v2.0 mirna expression beadchip microarray platform - by Bioz Stars, 2026-08
    90/100 stars

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    1) Product Images from "MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview"

    Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview

    Journal: Molecular Neurobiology

    doi: 10.1007/s12035-014-8668-y

    The biogenesis of miRNA requires RNA polymerase II/III for the transcription of pri-miRNA. The pri-miRNA product is then cleaved by the Drosha-DGCR8 complex into pre-miRNA. The pre-miRNA is exported to the cytoplasm by Exportin-5 in the presence of Ran-GTP co-factor. Once in the cytoplasm, the pre-miRNA is cleaved by the Dicer-TRBP complex into a miRNA duplex, which is unwound into two products: a guide strand bound to Ago2, which is incorporated into the RISC, and a passenger strand, which is degraded. Finally, the miRNA binds to its target mRNAs resulting in mRNA target cleavage, translational repression, or mRNA decay. A more novel fate of the miRNAs is the selective secretion via microvesicles or exosomes. Ran = Ras-related nuclear protein; GTP = guanosine-5′-triphosphate; TRBP = TAR (HIV-1) RNA binding protein; Ago2 = Argonaute protein 2; RISC = RNA-induced silencing complex
    Figure Legend Snippet: The biogenesis of miRNA requires RNA polymerase II/III for the transcription of pri-miRNA. The pri-miRNA product is then cleaved by the Drosha-DGCR8 complex into pre-miRNA. The pre-miRNA is exported to the cytoplasm by Exportin-5 in the presence of Ran-GTP co-factor. Once in the cytoplasm, the pre-miRNA is cleaved by the Dicer-TRBP complex into a miRNA duplex, which is unwound into two products: a guide strand bound to Ago2, which is incorporated into the RISC, and a passenger strand, which is degraded. Finally, the miRNA binds to its target mRNAs resulting in mRNA target cleavage, translational repression, or mRNA decay. A more novel fate of the miRNAs is the selective secretion via microvesicles or exosomes. Ran = Ras-related nuclear protein; GTP = guanosine-5′-triphosphate; TRBP = TAR (HIV-1) RNA binding protein; Ago2 = Argonaute protein 2; RISC = RNA-induced silencing complex

    Techniques Used: RNA Binding Assay

    Studies performed on dataset obtained from public databases
    Figure Legend Snippet: Studies performed on dataset obtained from public databases

    Techniques Used: Biomarker Discovery, In Vitro, Cell Culture, Activity Assay, Standard Deviation, Expressing, Software, Mutagenesis, Amplification

    Studies performed on independent tissue cohorts
    Figure Legend Snippet: Studies performed on independent tissue cohorts

    Techniques Used: Control, Biomarker Discovery, In Situ Hybridization, In Vitro, In Situ, Methylation, Expressing, Invasion Assay, Transfection, Amplification, Migration, Luciferase, Transwell Assay, Wound Healing Assay

    miRNAs reported to be protective or risk-associated
    Figure Legend Snippet: miRNAs reported to be protective or risk-associated

    Techniques Used: Expressing

    miRNA signatures correlating with survival in GBM
    Figure Legend Snippet: miRNA signatures correlating with survival in GBM

    Techniques Used:



    Similar Products

    human v2.0 mirna expression beadchip microarray platform  (Illumina Inc)
    90
    Illumina Inc human v2.0 mirna expression beadchip microarray platform
    The biogenesis of <t>miRNA</t> requires RNA polymerase II/III for the transcription of pri-miRNA. The pri-miRNA product is then cleaved by the Drosha-DGCR8 complex into pre-miRNA. The pre-miRNA is exported to the cytoplasm by Exportin-5 in the presence of Ran-GTP co-factor. Once in the cytoplasm, the pre-miRNA is cleaved by the Dicer-TRBP complex into a miRNA duplex, which is unwound into two products: a guide strand bound to Ago2, which is incorporated into the RISC, and a passenger strand, which is degraded. Finally, the miRNA binds to its target mRNAs resulting in mRNA target cleavage, translational repression, or mRNA decay. A more novel fate of the miRNAs is the selective secretion via microvesicles or exosomes. Ran = Ras-related nuclear protein; GTP = guanosine-5′-triphosphate; TRBP = TAR (HIV-1) RNA binding protein; Ago2 = Argonaute protein 2; RISC = RNA-induced silencing complex
    Human V2.0 Mirna Expression Beadchip Microarray Platform, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+v2%2E0+mirna+expression+beadchip+microarray+platform/pmc04225053-216-17-16?v=Illumina+Inc
    Average 90 stars, based on 1 article reviews
    human v2.0 mirna expression beadchip microarray platform - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    The biogenesis of miRNA requires RNA polymerase II/III for the transcription of pri-miRNA. The pri-miRNA product is then cleaved by the Drosha-DGCR8 complex into pre-miRNA. The pre-miRNA is exported to the cytoplasm by Exportin-5 in the presence of Ran-GTP co-factor. Once in the cytoplasm, the pre-miRNA is cleaved by the Dicer-TRBP complex into a miRNA duplex, which is unwound into two products: a guide strand bound to Ago2, which is incorporated into the RISC, and a passenger strand, which is degraded. Finally, the miRNA binds to its target mRNAs resulting in mRNA target cleavage, translational repression, or mRNA decay. A more novel fate of the miRNAs is the selective secretion via microvesicles or exosomes. Ran = Ras-related nuclear protein; GTP = guanosine-5′-triphosphate; TRBP = TAR (HIV-1) RNA binding protein; Ago2 = Argonaute protein 2; RISC = RNA-induced silencing complex

    Journal: Molecular Neurobiology

    Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview

    doi: 10.1007/s12035-014-8668-y

    Figure Lengend Snippet: The biogenesis of miRNA requires RNA polymerase II/III for the transcription of pri-miRNA. The pri-miRNA product is then cleaved by the Drosha-DGCR8 complex into pre-miRNA. The pre-miRNA is exported to the cytoplasm by Exportin-5 in the presence of Ran-GTP co-factor. Once in the cytoplasm, the pre-miRNA is cleaved by the Dicer-TRBP complex into a miRNA duplex, which is unwound into two products: a guide strand bound to Ago2, which is incorporated into the RISC, and a passenger strand, which is degraded. Finally, the miRNA binds to its target mRNAs resulting in mRNA target cleavage, translational repression, or mRNA decay. A more novel fate of the miRNAs is the selective secretion via microvesicles or exosomes. Ran = Ras-related nuclear protein; GTP = guanosine-5′-triphosphate; TRBP = TAR (HIV-1) RNA binding protein; Ago2 = Argonaute protein 2; RISC = RNA-induced silencing complex

    Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Illumina Human v2.0 miRNA Expression BeadChip microarray platform [ , – ].

    Techniques: RNA Binding Assay

    Studies performed on dataset obtained from public databases

    Journal: Molecular Neurobiology

    Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview

    doi: 10.1007/s12035-014-8668-y

    Figure Lengend Snippet: Studies performed on dataset obtained from public databases

    Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Illumina Human v2.0 miRNA Expression BeadChip microarray platform [ , – ].

    Techniques: Biomarker Discovery, In Vitro, Cell Culture, Activity Assay, Standard Deviation, Expressing, Software, Mutagenesis, Amplification

    Studies performed on independent tissue cohorts

    Journal: Molecular Neurobiology

    Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview

    doi: 10.1007/s12035-014-8668-y

    Figure Lengend Snippet: Studies performed on independent tissue cohorts

    Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Illumina Human v2.0 miRNA Expression BeadChip microarray platform [ , – ].

    Techniques: Control, Biomarker Discovery, In Situ Hybridization, In Vitro, In Situ, Methylation, Expressing, Invasion Assay, Transfection, Amplification, Migration, Luciferase, Transwell Assay, Wound Healing Assay

    miRNAs reported to be protective or risk-associated

    Journal: Molecular Neurobiology

    Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview

    doi: 10.1007/s12035-014-8668-y

    Figure Lengend Snippet: miRNAs reported to be protective or risk-associated

    Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Illumina Human v2.0 miRNA Expression BeadChip microarray platform [ , – ].

    Techniques: Expressing

    miRNA signatures correlating with survival in GBM

    Journal: Molecular Neurobiology

    Article Title: MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview

    doi: 10.1007/s12035-014-8668-y

    Figure Lengend Snippet: miRNA signatures correlating with survival in GBM

    Article Snippet: However, four studies used the Chinese Glioma Genome Atlas (CGGA) ( http://www.cgga.org.cn ), which uses the Illumina Human v2.0 miRNA Expression BeadChip microarray platform [ , – ].

    Techniques: